Little Evidence of Zika Virus Infection in Wild Long-Tailed Macaques, Peninsular Malaysia

Emerg Infect Dis. 2019 Feb;25(2):374-376. doi: 10.3201/eid2502.180258.

Abstract

We tested a sample of 234 wild long-tailed macaques (Macaca fascicularis) trapped in Peninsular Malaysia in 2009, 2010, and 2016 for Zika virus RNA and antibodies. None were positive for RNA, and only 1.3% were seropositive for neutralizing antibodies. Long-tailed macaques are unlikely to be reservoirs for Zika virus in Malaysia.

Keywords: DENV-1; DENV-2; FRNT; Macaca fascicularis; Malaysia; PRNT; Peninsular Malaysia; Zika virus; dengue virus; long-tailed macaques; macaque; neutralizing antibodies; nonhuman primates; plaque reduction neutralization test; seroprevalence; sylvatic cycle; viruses.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Animals, Wild
  • Macaca fascicularis
  • Malaysia / epidemiology
  • Monkey Diseases / epidemiology*
  • Monkey Diseases / virology*
  • RNA, Viral
  • Serogroup
  • Zika Virus Infection / veterinary*
  • Zika Virus* / classification
  • Zika Virus* / genetics

Substances

  • RNA, Viral