RETRACTED: Brazilein induces apoptosis and G1/G0 phase cell cycle arrest by up-regulation of miR-133a in human vestibular schwannoma cells

Exp Mol Pathol. 2019 Apr:107:95-101. doi: 10.1016/j.yexmp.2018.12.010. Epub 2019 Jan 2.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Given the comments of Dr Elisabeth Bik regarding this article “... the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy/pasted from other sources, or computer generated”, the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.

Keywords: Acoustic neuroma; Brazilein; G1/G0 cell cycle; MAPK and JNK pathways; miR-133a.

Publication types

  • Retracted Publication

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects*
  • Benzopyrans / pharmacology*
  • Cell Cycle Checkpoints / drug effects
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Humans
  • Indenes / pharmacology*
  • MicroRNAs / biosynthesis*
  • MicroRNAs / drug effects
  • Neuroma, Acoustic / pathology*
  • Resting Phase, Cell Cycle / drug effects
  • Up-Regulation

Substances

  • Antineoplastic Agents
  • Benzopyrans
  • Indenes
  • MIRN133 microRNA, human
  • MicroRNAs
  • brazilein