Data on ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications

Berney Peng; Mohammad Almeqdadi; Fabrice Laroche; Shajesh Palantavida; Maxim Dokukin; Jatin Roper; Omer H Yilmaz; Hui Feng; Igor Sokolov

doi:10.1016/j.dib.2018.12.030

Data on ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications

Data Brief. 2018 Dec 18:22:383-391. doi: 10.1016/j.dib.2018.12.030. eCollection 2019 Feb.

Authors

Berney Peng¹, Mohammad Almeqdadi^{2

3

4}, Fabrice Laroche⁵, Shajesh Palantavida⁶, Maxim Dokukin⁶, Jatin Roper^{3

4}, Omer H Yilmaz³, Hui Feng⁵, Igor Sokolov^{1

6

7}

Affiliations

¹ Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
² Department of Medicine, St. Elizabeth׳s Medical Center, Boston, MA, USA.
³ The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA.
⁴ Department of Medicine, Tufts Medical Center, Boston, MA, USA.
⁵ Departments of Pharmacology and Medicine, The Center for Cancer Research, Section of Hematology and Medical Oncology, Boston University School of Medicine, Boston, MA, USA.
⁶ Department of Mechanical Engineering, Tufts University, Medford, MA, USA.
⁷ Department of Physics, Tufts University, Medford, MA, USA.

Abstract

Characterization data of fluorescent nanoparticles made of cellulose acetate (CA-dots) are shown. The data in this article accompanies the research article "Ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications" [1]. The measurements and calculation of brightness of individual CA-dots are presented. The description of conjugation procedure Pluronic F127-Folic Acid copolymer and folic acid is shown. Identification of composition of CA dots using Raman and absorbance spectroscopy is demonstrated. The methods for image analysis of efficiency of CA-dot targeting of epithelial tumors xenografted in zebrafish is presented.

Abstract

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