Abstract
Neisseria meningitidis sequence type 11 is an emerging cause of urethritis. We demonstrate by using whole-genome sequencing orogenital transmission of a N. meningitidis sequence type 11 isolate causing urethritis in a monogamous couple of men who have sex with men. These results suggest dissemination of this clonal complex among low-risk patients.
Keywords:
Neisseria meningitidis; ST11; bacteria; clonal complex; men who have sex with men; monogamous couple; orogenital transmission; sequence type 11; sexually transmitted infections; urethritis; whole-genome sequencing.
MeSH terms
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Acute Disease
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Anti-Bacterial Agents / administration & dosage*
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Azithromycin / administration & dosage
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Ceftriaxone / administration & dosage
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Communicable Diseases, Emerging / drug therapy
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Communicable Diseases, Emerging / microbiology
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Communicable Diseases, Emerging / transmission*
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Humans
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Injections, Intramuscular
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Male
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Meningococcal Infections / drug therapy
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Meningococcal Infections / microbiology
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Meningococcal Infections / transmission*
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Neisseria meningitidis / genetics*
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Neisseria meningitidis / isolation & purification
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Sexual and Gender Minorities
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Sexually Transmitted Diseases / drug therapy
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Sexually Transmitted Diseases / microbiology
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Sexually Transmitted Diseases / transmission*
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Treatment Outcome
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Urethritis / drug therapy
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Urethritis / microbiology*
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Whole Genome Sequencing
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Young Adult
Substances
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Anti-Bacterial Agents
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Ceftriaxone
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Azithromycin