Successful treatment of hemorrhagic bullous Henoch-Schonlein purpura with intravenous immunoglobulins

Pediatr Dermatol. 2019 Jan;36(1):e34-e36. doi: 10.1111/pde.13715. Epub 2018 Dec 18.

Abstract

Henoch-Schonlein purpura (HSP) is the most common systemic vasculitis in childhood. There is no consensus about the management for isolated cutaneous manifestations in HSP. We describe a case of HSP presenting with severe skin lesions that did not respond to standard therapy with corticosteroids. The 11-year-old child was treated with intravenous immunoglobulins, which induced rapid and persistent resolution of symptomatology.

Keywords: Henoch-Schonlein purpura; hemorrhagic bullous; intravenous immunoglobulin; treatment.

Publication types

  • Case Reports

MeSH terms

  • Blister / etiology
  • Child
  • Female
  • Glucocorticoids / therapeutic use
  • Hemorrhage / etiology
  • Humans
  • IgA Vasculitis / complications
  • IgA Vasculitis / diagnosis
  • IgA Vasculitis / therapy*
  • Immunoglobulins, Intravenous / therapeutic use*
  • Skin / pathology

Substances

  • Glucocorticoids
  • Immunoglobulins, Intravenous