Detection of three novel atypical porcine pestivirus strains in newborn piglets with congenital tremor in southern China

Infect Genet Evol. 2019 Mar:68:54-57. doi: 10.1016/j.meegid.2018.12.008. Epub 2018 Dec 6.

Abstract

Atypical porcine pestivirus (APPV) have been discovered in swine herds from three provinces in China, suggesting a wide distribution in China. This study reports the occurrence of three novel APPV strains in China. They were detected from newborn piglets with clinical signs of congenital tremors (CT) in Guangdong Province, China. The complete genomic sequences of three novel APPV strains exhibited only 80.5%-84.1% nucleotide sequences homology with other APPV reference sequences available in GenBank. Phylogenetic analysis showed that these novel APPV strains formed independent branch from the American, German, Netherlandish, Australian and other Chinese strains. These results will help us better understand the epidemiology and genetic characteristics of APPV in China.

Keywords: Atypical porcine pestivirus; Congenital tremor; Novel; Phylogenetic analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • China / epidemiology
  • Genes, Viral
  • Genetic Variation
  • Genome, Viral
  • Pestivirus Infections / veterinary*
  • Pestivirus* / classification
  • Pestivirus* / genetics
  • Phylogeny
  • Swine
  • Swine Diseases / epidemiology*
  • Swine Diseases / virology*
  • Tremor / epidemiology*
  • Tremor / etiology