[Differential diagnosis for breast ductal carcinoma in situ and plasma cell mastitis by magnetic resonance imaging]

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Oct 28;43(10):1123-1130. doi: 10.11817/j.issn.1672-7347.2018.10.013.
[Article in Chinese]

Abstract

To investigate the magnetic resonance imaging (MRI) features for ductal carcinoma in situ (DCIS) and plasma cell mastitis (PCM) , and to improve diagnostic accuracy for DCIS and PCM. Methods: The MRI morphology confirmed by surgical pathology and dynamic enhancement for 35 patients with DCIS and 45 patients with PCM were retrospectively analyzed, which included T1 pre-scan high signal, enhanced distribution characteristics, internal strengthening mode, whether centrifugation or centripetal diffusion, dynamic enhancement curve morphology, diffusion-weighted imaging (DWI) signal characteristics, and apparent diffusion coefficient (ADC) values. Results: The segmental distribution, clustered ring, T1 pre-catheters diffusion and the dynamic delayed concentric diffusion were more common in DCIS than those in PCM (P<0.05). Regional distribution, internal heterogeneity enhancement, and enhanced delay period eccentric diffusion were more common in PCM than those in DCIS (P<0.05). In the PCM group, nipple repertoire, DWI center high signal, adjacent skin thickening, and sinus formation were significantly higher than those in the DCIS group (P<0.05). Conclusion: Both DCIS and PCM show a non-mass like enhancement on MRI. Images in DCIS mostly show duct-like, branch-like and segment-like distribution. The internal enhancement mode is centripetal diffusion. Images in PCM mostly show regional distribution, and the inside displays heterogeneity enhancement with the adjacent skin thickening and nipple subsided.

目的:探讨乳腺导管原位癌(ductal carcinoma in situ,DCIS)与浆细胞性乳腺炎(plasma cell mastitis,PCM)的磁共振成像(magnetic resonance imaging,MRI)表现特征,提高DCIS和PCM的诊断正确率。方法:回顾性分析经病理证实的35例DCIS和45例PCM患者的MRI图像,从2种病变的T1预扫高信号、强化分布特征、内部强化方式、是否离心或向心扩散、动态增强曲线形态、弥散加权成像(diffusion-weighted image,DWI)信号特点、表观扩散系数值进行比较和分析。结果:DCIS多见段样分布,成簇环状强化,T1预扫导管分支状高信号,动态增强延迟向心性扩散;PCM多见区域性分布,内部不均质强化及增强延迟离心扩散;PCM组乳头内陷、DWI中心高信号,邻近皮肤增厚及窦道形成均明显高于DCIS组(P<0.05)。结论:DCIS与PCM在MRI上均表现为非肿块样强化方式;DCIS多呈导管分支样及段样分布,内部强化方式呈向心性扩散;PCM多为区域分布,内部呈不均质强化伴邻近皮肤增厚、乳头内陷,部分DWI中心高信号对应强化环的中心。.

MeSH terms

  • Breast Neoplasms / diagnostic imaging*
  • Carcinoma, Ductal, Breast / diagnostic imaging*
  • Contrast Media
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Mastitis / diagnostic imaging*
  • Plasma Cells / pathology
  • Retrospective Studies

Substances

  • Contrast Media