Intracholecystic papillary-tubular neoplasm of the gallbladder originating in the cystic duct with extensive intraepithelial progress in the common bile duct

Clin J Gastroenterol. 2019 Jun;12(3):197-204. doi: 10.1007/s12328-018-0927-4. Epub 2018 Nov 30.

Abstract

A 59-year-old man with anorexia who had a history of cholecystectomy was referred to our hospital. Imaging examinations revealed a contrast-enhanced tumor in the residual cystic duct and a part of the common bile duct. Endoscopic retrograde cholangiopancreatography and peroral-cholangioscopy showed a papillary tumor with movement and a change in the shape. Under a diagnosis of primary cystic duct cancer, subtotal stomach-preserving pancreaticoduodenectomy was performed. The microscopic examination of a resected specimen revealed intracholecystic papillary-tubular neoplasm located in the residual cystic duct, forming a polypoid protrusion to the common bile duct and extensive intraepithelial progress in the common bile duct.

Keywords: Gallbladder cancer; ICPN (intracholecystic papillary-tubular neoplasm); IPNB (intraductal papillary neoplasm of bile duct); Intraepithelial progress; POCS (peroral cholangioscopy).

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Carcinoma in Situ / pathology*
  • Cholangiopancreatography, Endoscopic Retrograde
  • Common Bile Duct
  • Cystic Duct / pathology*
  • Gallbladder Neoplasms / diagnostic imaging
  • Gallbladder Neoplasms / pathology*
  • Gallbladder Neoplasms / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Pancreaticoduodenectomy
  • Tomography, X-Ray Computed