CrossTalk proposal: The mouse SuHx model is a good model of pulmonary arterial hypertension

J Physiol. 2019 Feb;597(4):975-977. doi: 10.1113/JP275864. Epub 2018 Nov 29.
No abstract available

Keywords: Hypoxia; Mouse; Sugen; Vascular remodelling; pulmonary hypertension; ventricular dysfunction.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiogenesis Inhibitors / toxicity
  • Animals
  • Disease Models, Animal*
  • Hypertension, Pulmonary / etiology
  • Hypertension, Pulmonary / pathology
  • Hypertension, Pulmonary / physiopathology*
  • Hypoxia / complications*
  • Indoles / toxicity
  • Mice
  • Pyrroles / toxicity
  • Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors*

Substances

  • Angiogenesis Inhibitors
  • Indoles
  • Pyrroles
  • Semaxinib
  • Receptors, Vascular Endothelial Growth Factor