Synthesis of Polycyclic Aromatic Hydrocarbons (PAHs) via a Transient Directing Group

Org Lett. 2018 Dec 7;20(23):7620-7623. doi: 10.1021/acs.orglett.8b03359. Epub 2018 Nov 20.

Abstract

In this work, an efficient synthetic route was developed to construct PAHs with diverse shape, width, and edge topology. The precursors of PAHs were obtained by using a direct arylation of arenes via a transient ligand-directed C-H functionalization strategy and the cycloaromatization was readily achieved by using a Brønsted acid catalyst. This novel route provides an opportunity to build up PAHs in a highly efficient manner.

Publication types

  • Research Support, Non-U.S. Gov't