Alcohol Use Disorders in Alcoholic Liver Disease

Clin Liver Dis. 2019 Feb;23(1):55-69. doi: 10.1016/j.cld.2018.09.004.

Abstract

Alcohol use disorder (AUD) is common in alcoholic liver disease (ALD) and intrinsic to its pathophysiology. Optimal treatment requires a multidisciplinary team approach and a working alliance between patients and providers. Diagnosing AUD involves a combination of thorough history taking, physical examination, screening questionnaires, and alcohol biomarkers. Alcohol biomarkers have advantages and limitations of use of which clinicians should be aware. AUD treatment is effective, multifaceted, and can be tailored to each individual. Available treatment modalities are myriad: motivational enhancement therapy, cognitive behavior therapy, 12-step facilitation, group therapies, intensive outpatient programs, inpatient and residential treatment, and relapse prevention medications.

Keywords: Addiction; Alcohol dependence; Biomarkers; Multidisciplinary care.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alcohol Abstinence
  • Alcohol Deterrents / therapeutic use
  • Alcoholism / complications
  • Alcoholism / diagnosis
  • Alcoholism / metabolism
  • Alcoholism / rehabilitation*
  • Biomarkers / metabolism
  • Humans
  • Liver Diseases, Alcoholic / etiology
  • Liver Diseases, Alcoholic / therapy*

Substances

  • Alcohol Deterrents
  • Biomarkers