Pediatric Central Nervous System Tumors: State-of-the-Art and Debated Aspects

Front Pediatr. 2018 Nov 1:6:309. doi: 10.3389/fped.2018.00309. eCollection 2018.

Abstract

Pediatric neuro-oncology surgery continues to progress in sophistication, largely driven by advances in technology used to aid the following aspects of surgery: operative planning (advanced MRI techniques including fMRI and DTI), intraoperative navigation [preoperative MRI, intra-operative MRI (ioMRI) and intra-operative ultrasound (ioUS)], tumor visualization (microscopy, endoscopy, fluorescence), tumor resection techniques (ultrasonic aspirator, micro-instruments, micro-endoscopic instruments), delineation of the resection extent (ioMRI, ioUS, and fluorescence), and intraoperative safety (neurophysiological monitoring, ioMRI). This article discusses the aforementioned technological advances, and their multimodal use to optimize safe pediatric neuro-oncology surgery.

Keywords: intraoperative magnetic resonance imaging; neurooncology; pediatric brain tumors; pediatric neuroimaging; technology in surgery.

Publication types

  • Review