1 Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
2 Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.
3 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
4 National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK.
5 MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
6 Department of Mathematics, Imperial College London, London, UK.
7 Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
8 Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA.
9 Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.
10 Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.
11 Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.
12 Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA.
13 Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.
14 VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.
15 Nephrology Section, Memphis VA Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA.
16 Estonian Genome Center, University of Tartu, Tartu, Estonia.
17 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
18 Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
19 MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.
20 Department of Neurology, Bordeaux University Hospital, Bordeaux, France.
21 Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France.
22 Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA.
23 Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
24 Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia.
25 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
26 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
27 MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
28 MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
29 Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.
30 NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK.
31 Wellcome Trust Sanger Institute, Hinxton, UK.
32 Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.
33 Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan.
34 Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
35 Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada.
36 Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.
37 University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands.
38 University of Lille, Inserm, Centre Hosp. Univ. Lille, Institut Pasteur de Lille, UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, Lille, France.
39 University of Dundee, Ninewells Hospital & Medical School, Dundee, UK.
40 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
41 Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
42 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
43 Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
44 Imperial Clinical Trials Unit, London, UK.
45 School of Medicine, University College Dublin, Dublin, Ireland.
46 Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
47 International Centre for Circulatory Health, Imperial College London, London, UK.
48 Center for Statistical Genetics, Department of Biostatistics, SPH II, Washington Heights, Ann Arbor, MI, USA.
49 Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
50 Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
51 Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
52 Sema4, a Mount Sinai venture, Stamford, CT, USA.
53 Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
54 Department of Health Sciences, University of Leicester, Leicester, UK.
55 Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
56 Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.
57 Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
58 Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands.
59 The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
60 Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
61 NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
62 Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
63 Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
64 Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.
65 Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
66 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
67 Department of Cardiology, Ealing Hospital, Middlesex, UK.
68 Imperial College Healthcare NHS Trust, London, UK.
69 Centre for Brain Research, Indian Institute of Science, Bangalore, India.
70 Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Napoli, Italy.
71 IRCCS Neuromed, Pozzilli, Isernia, Italy.
72 Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
73 Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA.
74 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
75 Department of Psychology, University of Edinburgh, Edinburgh, UK.
76 Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
77 Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
78 Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.
79 Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA.
80 Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
81 DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
82 Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland.
83 CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain.
84 Faculty of Medicine, Universitat de Vic-Central de Catalunya, Vic, Spain.
85 Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden.
86 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
87 Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK.
88 Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
89 Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden.
90 Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden.
91 Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
92 Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden.
93 Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
94 Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
95 German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
96 Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK.
97 Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
99 The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
100 Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA.
101 Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
102 Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.
103 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
104 Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
105 Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
106 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
107 National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
108 The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
109 Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
110 Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
111 Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia.
112 School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.
113 Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, the Netherlands.
114 Biocenter Oulu, University of Oulu, Oulu, Finland.
115 Center For Life-course Health Research, University of Oulu, Oulu, Finland.
116 Unit of Primary Care, Oulu University Hospital, Oulu, Oulu, Finland.
117 Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA.
118 Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
119 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
120 Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.
121 Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
122 Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
123 Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
124 Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
125 Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK.
126 Data Science Institute and Lancaster Medical School, Lancaster, UK.
127 Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.
128 National Heart and Lung Institute, Imperial College London, London, UK.
129 Swiss Institute of Bioinformatics, Lausanne, Switzerland.
130 Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
131 Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
132 Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
133 Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden.
134 Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
135 Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
136 Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.
137 Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.
138 University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland.
139 Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.
140 Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands.
141 Department of Biostatistics, University of Liverpool, Liverpool, UK.
142 Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
143 Data Tecnica International, Glen Echo, MD, USA.
144 Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.
145 Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland.
146 Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
147 Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
148 SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
149 British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
150 Department of Medicine, Columbia University Medical Center, New York, NY, USA.
151 Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
152 The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
153 University of Tartu, Tartu, Estonia.
154 German Center for Cardiovascular Disease Research (DZHK), partner site Munich, Neuherberg, Germany.
155 Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia.
156 Department of Neurology, General Central Hospital, Bolzano, Italy.
157 Department of Neurology, University of Lübeck, Lübeck, Germany.
158 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
159 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
160 Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China.
161 Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany.
162 Department of Biostatistics, University of Washington, Seattle, WA, USA.
163 Harvard Medical School, Boston, MA, USA.
164 Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
165 Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
166 The New York Academy of Medicine, New York, NY, USA.
167 Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
168 Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.
169 Population Health Research Institute, St George's, University of London, London, UK.
170 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
171 Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
172 Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
173 Dasman Diabetes Institute, Dasman, Kuwait.
174 Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.
175 Department of Public Health, University of Helsinki, Helsinki, Finland.
176 Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
177 Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.
178 Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
179 Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
180 Department of Internal Medicine, University Hospital, CHUV, Lausanne, Switzerland.
181 Experimental Genetics Division, Sidra Medical and Research Center, Doha, Qatar.
182 Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
183 Department of Biology, Faculty of Medicine, University of Split, Split, Croatia.
184 The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.
185 Division of Cardiology, University Hospital, Basel, Switzerland.
186 Division of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
187 Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Cagliari, Italy.
188 Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
189 Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
190 Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
191 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
192 Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein.
193 Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.
194 University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
195 Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
196 Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
197 Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
198 Tennessee Valley Healthcare System (Nashville VA) & Vanderbilt University, Nashville, TN, USA.
199 VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
200 Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.
201 Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
202 Department of Epidemiology and Biostatistics, Imperial College London, London, UK. p.elliott@imperial.ac.uk.
203 MRC-PHE Centre for Environment and Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.
204 National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. p.elliott@imperial.ac.uk.
205 UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. p.elliott@imperial.ac.uk.
206 Health Data Research-UK London substantive site, London, UK. p.elliott@imperial.ac.uk.
207 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.
208 National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.
In the version of this article originally published, the name of author Martin H. de Borst was coded incorrectly in the XML. The error has now been corrected in the HTML version of the paper.