Progressive multifocal leukoencephalopathy developing after obinutuzumab treatment for chronic lymphocytic leukemia

Ann Hematol. 2019 Jun;98(6):1509-1510. doi: 10.1007/s00277-018-3552-x. Epub 2018 Nov 13.

Authors

Vlatko Pejsa^{1

2}, Marko Lucijanic³, Zeljko Jonjic³, Zeljko Prka³, Gorana Vukorepa⁴

Affiliations

¹ Department of Hematology, University Hospital Dubrava, Av. Gojka Suska 6, 10000, Zagreb, Croatia. vpejsa@kbd.hr.
² School of Medicine, University of Zagreb, Zagreb, Croatia. vpejsa@kbd.hr.
³ Department of Hematology, University Hospital Dubrava, Av. Gojka Suska 6, 10000, Zagreb, Croatia.
⁴ Neurology Department, University Hospital Dubrava, Zagreb, Croatia.

PMID: 30421169
DOI: 10.1007/s00277-018-3552-x

No abstract available

Publication types

Letter

MeSH terms

Antibodies, Monoclonal, Humanized / administration & dosage
Antibodies, Monoclonal, Humanized / adverse effects*
Antineoplastic Agents, Immunological / administration & dosage
Antineoplastic Agents, Immunological / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Brain / pathology
Brain / virology
Chlorambucil / administration & dosage
Disease Progression
Female
Humans
Immunosuppressive Agents / administration & dosage
Immunosuppressive Agents / adverse effects*
JC Virus / isolation & purification
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
Leukoencephalopathy, Progressive Multifocal / diagnostic imaging
Leukoencephalopathy, Progressive Multifocal / etiology*
Leukoencephalopathy, Progressive Multifocal / virology
Magnetic Resonance Imaging
Middle Aged
Neuroimaging
Vision Disorders / etiology
Vision Disorders / virology

Substances

Antibodies, Monoclonal, Humanized
Antineoplastic Agents, Immunological
Immunosuppressive Agents
Chlorambucil
obinutuzumab