Silent T2* and T2 encoding using ZTE combined with BURST

Magn Reson Med. 2019 Apr;81(4):2277-2287. doi: 10.1002/mrm.27552. Epub 2018 Nov 2.

Abstract

Purpose: To obtain T2* and T2 -weighted images as well as quantitative T2* , T2 , and susceptibility maps with a novel, silent 3D imaging method, which combines zero-echo-time (ZTE) imaging with gradient- and spin-echo BURST encoding.

Methods: After a segment of standard ZTE encoding with multiple 3D radial k-space spokes, the direction of traversing k-space is reversed while excitation is switched off. This recalls gradient echoes for each spoke/excitation. This results in multiple images: one FID image from ZTE and multiple BURST echo images at different echo times weighted by a T2* decay. By adding a pair of 180° pulses with an appropriate wait period, it is also possible to obtain spin echoes, leading to T2 -weighted images. Data is reconstructed using standard 3D gridding and Fourier transformation. In vivo feasibility was demonstrated by imaging the brain of multiple healthy volunteers.

Results: It is possible to acquire high-quality T2* - and T2 -weighted brain images in a silent manner. From images acquired with gradient-echo ZTE-BURST, it is possible to extract quantitative T2* and magnetic susceptibility maps, whereas the spin echo version yields T2 maps.

Conclusion: ZTE combined with BURST enables silent acquisition of T2* - and T2 -weighted images with good image quality.

Keywords: BURST; ZTE; quantitative MRI.

MeSH terms

  • Acoustics
  • Adult
  • Algorithms
  • Brain / diagnostic imaging*
  • Computer Simulation
  • Fourier Analysis
  • Healthy Volunteers
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Imaging, Three-Dimensional
  • Magnetic Resonance Imaging*
  • Phantoms, Imaging
  • Software