Study on the influence of optical absorption on polarization characterization of tissues

J Biomed Opt. 2018 Oct;23(12):1-9. doi: 10.1117/1.JBO.23.12.121609.

Abstract

Absorption effect is a basic optical phenomenon and an important feature in tissue imaging and characterization. Based on our Monte Carlo simulation on the anisotropic tissue model (sphere-cylinder birefringence model), combined with our experiments of tissue phantoms, we demonstrate the influence of absorption effect on Mueller matrix and particularly on depolarization, linear retardance, and diattenuation parameters. The simulation and experimental results show a good consistency on the suppressed depolarization and scatterering induced retardance, and the enhanced diattenuation caused by the absorption, and also indicate the birefringence induced retardance insensitive to the absorption. Study of the phase function of different incident polarized lights and the distribution of scattering number gives a preliminary explanation about the above results.

Keywords: Mueller matrix decomposition; absorption; polarization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anisotropy
  • Birefringence
  • Computer Simulation
  • Light
  • Linear Models
  • Microscopy, Polarization
  • Microspheres
  • Monte Carlo Method
  • Nephelometry and Turbidimetry
  • Optics and Photonics*
  • Phantoms, Imaging
  • Photons
  • Polystyrenes / chemistry
  • Scattering, Radiation

Substances

  • Polystyrenes