Two cases of primary cutaneous nocardiosis caused by intralesional injection

Dermatol Ther. 2019 Jan;32(1):e12775. doi: 10.1111/dth.12775. Epub 2018 Nov 19.

Abstract

Nocardiosis is a rare localized or systemic suppurative disease caused by the actinomycete Nocardia species. The respiratory tract is the most common site of infection, but primary cutaneous nocardiosis can also be induced by direct inoculation. Nocardiosis is usually reported in immunocompromised patients, such as those with human immunodeficiency virus (HIV) infection, chronic obstructive pulmonary disease, autoimmune diseases, cancer, or in those who have had organ transplantation or corticosteroid administration. However, it can also affect individuals with no serious underlying condition. We reported two cases of primary cutaneous nocardiosis in immunocompetent patients after intralesional injection of steroid.

Keywords: Nocardia infections; Nocardiosis; injections.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Bacteriological Techniques
  • Biopsy
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects*
  • Humans
  • Injections, Intralesional
  • Middle Aged
  • Nocardia Infections / chemically induced*
  • Nocardia Infections / diagnosis
  • Nocardia Infections / microbiology
  • Nocardia Infections / transmission
  • Risk Factors
  • Skin / drug effects*
  • Skin / microbiology
  • Skin / pathology
  • Treatment Outcome
  • Triamcinolone / administration & dosage
  • Triamcinolone / adverse effects*

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Triamcinolone