Using sacral nerve modulation to improve continence and quality of life in patients suffering from low anterior resection syndrome

ANZ J Surg. 2018 Nov;88(11):E787-E791. doi: 10.1111/ans.14871. Epub 2018 Oct 22.

Abstract

Background: Sphincter preserving surgery for the treatment of rectal cancer is very often feasible, avoiding a permanent colostomy. It is well recognized that a large proportion of patients will experience altered bowel habit following low anterior resection (LAR). Faecal incontinence is a common symptom associated with LAR syndrome. The aim of this study is to evaluate the long-term improvement in continence and quality of life (QoL) in LAR patients treated with sacral nerve modulation.

Methods: Patients with ongoing faecal incontinence for >1 year after reversal of diverting ileostomy post ultra-LAR were selected for the study. Eligible patients underwent sacral nerve modulator implantation as a two-stage procedure. Bowel diaries and the Cleveland Clinic Faecal Incontinence Score were used to measure faecal incontinence and QoL.

Results: Twelve patients underwent permanent implantation of a sacral nerve stimulator. Median follow-up was 34 months (interquartile range (IQR) 20.25-62.5 months). The median improvement in faecal incontinence was 90% (IQR 76.25-98.75%) and the median improvement in patient QoL was 80% (IQR 71.25-93.75%). Patients who had previously been treated with biofeedback showed a median improvement in incontinence of 75% compared to 90% which was found in patients who had not had prior biofeedback treatment. The mean percentage improvement in patients with an internal anal sphincter defect was 80% compared to 90% seen in patients with an intact sphincter.

Conclusions: The results of this study suggest that sacral nerve modulation should be more widely considered as an effective treatment strategy for patients with faecal incontinence following LAR.

Keywords: incontinence; low anterior resection; quality of life; sacral nerve modulation.

Publication types

  • Evaluation Study

MeSH terms

  • Adenocarcinoma / surgery*
  • Aged
  • Electric Stimulation Therapy / instrumentation
  • Electric Stimulation Therapy / methods*
  • Fecal Incontinence / etiology
  • Fecal Incontinence / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Implantable Neurostimulators
  • Lumbosacral Plexus
  • Male
  • Middle Aged
  • Postoperative Complications / therapy*
  • Proctectomy* / methods
  • Quality of Life*
  • Rectal Neoplasms / surgery*
  • Retrospective Studies
  • Sacrum / innervation
  • Syndrome
  • Treatment Outcome