Keywords: C-reactive protein (CRP); Musculoskeletal Infection Society criteria (MSIS); antibiotic holiday; aspiration; biopsy; cement spacer; cement spacer aspiration; diagnostic accuracy; drug holiday; erythrocyte sedimentation rate (ESR); frozen section; imaging; inflammatory markers; international consensus meeting (ICM) criteria; intraoperative metrics; leukocyte esterase (LE) strip test; mycobacterial tuberculosis; reimplantation; reimplantation timing; serological markers; tubercular periprosthetic joint infection (PJI); tuberculosis; two-stage exchange arthroplasty.