No Evidence for Acquired Mutations Associated with Cytochrome bc1 Inhibitor Resistance in 13,559 Clinical Mycobacterium tuberculosis Complex Isolates

Antimicrob Agents Chemother. 2018 Dec 21;63(1):e01317-18. doi: 10.1128/AAC.01317-18. Print 2019 Jan.
No abstract available

Keywords: Mycobacterium tuberculosis; cytochrome bc1; lansoprazole; multidrug resistance; proton pump inhibitor.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antitubercular Agents / pharmacology*
  • Electron Transport Complex III / antagonists & inhibitors*
  • Humans
  • Lansoprazole / analogs & derivatives
  • Lansoprazole / pharmacology*
  • Microbial Sensitivity Tests
  • Mycobacterium tuberculosis / drug effects*
  • Mycobacterium tuberculosis / genetics*
  • Mycobacterium tuberculosis / isolation & purification
  • Tuberculosis, Multidrug-Resistant / drug therapy
  • Tuberculosis, Multidrug-Resistant / genetics*

Substances

  • Antitubercular Agents
  • Lansoprazole
  • Electron Transport Complex III