N,N'-Disuccinimidyl Carbonate: A Useful Reagent for Alkoxycarbonylation of Amines

Tetrahedron Lett. 1992 May 12;33(20):2781-2784. doi: 10.1016/S0040-4039(00)78856-3. Epub 2001 Mar 9.

Authors

Arun K Ghosh¹, Tien T Duong¹, Sean P McKee¹, Wayne J Thompson¹

Affiliation

¹ Department of Medicinal Chemistry, Merck Sharp & Dohme Research Laboratories West Point, Pennsylvania 19486.

Abstract

An efficient and mild method for alkoxycarbonylation of amines is described, utilizing commercially available N,N'-disuccinimidyl carbonate.

Grants and funding

R01 GM053386/GM/NIGMS NIH HHS/United States