Peripheral retinal nonperfusion using widefield imaging with von Hippel-Lindau disease

Jose S Pulido; Lauren A Dalvin; Timothy W Olsen; Fukutaro Mano; Michael Yu; Carol L Shields

doi:10.1186/s40942-018-0139-6

Peripheral retinal nonperfusion using widefield imaging with von Hippel-Lindau disease

Int J Retina Vitreous. 2018 Oct 3:4:36. doi: 10.1186/s40942-018-0139-6. eCollection 2018.

Authors

Jose S Pulido^{1

2}, Lauren A Dalvin^{1

3}, Timothy W Olsen¹, Fukutaro Mano¹, Michael Yu³, Carol L Shields³

Affiliations

¹ 1Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905 USA.
² 2Department of Molecular Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905 USA.
³ 3Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia, PA 19107 USA.

Abstract

Background: To describe a case of von Hippel-Lindau disease with peripheral retinal nonperfusion.

Case presentation: A 66-year-old female with known cerebellar and midbrain hemangioblastomas was evaluated for a retinal hemangioblastoma in the right eye. She underwent widefield fluorescein angiography, which showed hyperfluorescence localized to the hemangioblastoma surrounded by peripheral retinal nonperfusion in the same quadrant.

Conclusions: Further widefield imaging studies are required to determine if peripheral retinal nonperfusion is a common finding in von Hippel-Lindau disease.

Keywords: Eye; Fluorescein angiography; Hemangioblastoma; Nonperfusion; Tumor; von Hippel-Lindau.

Publication types

Case Reports