Burkitt Lymphoma Presenting With Intracardiac Mass and Tumor Thrombosis in the Anterior Mediastinum With Literature Review

J Pediatr Hematol Oncol. 2019 Apr;41(3):e197-e200. doi: 10.1097/MPH.0000000000001327.

Abstract

Burkitt lymphoma manifesting as an intracardiac mass is a rare entity. This report describes the case of a 10-year-old boy who presented with an intracardiac mass and tumor thrombosis in the anterior mediastinum that proved to be Burkitt lymphoma. The LMB-96 chemotherapy protocol was given and at the end of the treatment there was still residual mass. A biopsy was performed and the pathology revealed thymus tissue. The patient has been in complete remission for 3 months. Burkitt lymphoma has a short doubling time and an intracardiac lesion can become life threatening. Early recognition and prompt treatment are crucial in achieving optimal outcomes.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Burkitt Lymphoma / diagnosis*
  • Child
  • Heart Neoplasms / diagnosis
  • Heart Neoplasms / pathology*
  • Humans
  • Male
  • Mediastinum / pathology*
  • Neoplasms / complications
  • Remission Induction
  • Thrombosis / etiology*
  • Thymus Gland / pathology