Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions

Affiliations

• ¹ Institut de Biologie de l'École Normale Supérieure (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University, F-75005 Paris, France.
• ² Physics Department, East China Normal University, Shanghai, China.
• ³ Univ Lyon, ENS de Lyon, Univ Claude Bernard Lyon 1, CNRS, Laboratoire de Physique, F-69342 Lyon, France.
• ⁴ CNRS UMR5286, INSERM U1052, Centre de Recherche en Cancérologie de Lyon, F- 69008 Lyon, France.
• ⁵ Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette, France.
• ⁶ Centre Léon Bérard, F-69008 Lyon, France.
• ⁷ INSERM U1218, Institut Bergonié, F-33000 Bordeaux, France.
• ⁸ UMR 8126, Université Paris-Sud Paris-Saclay, CNRS, Institut Gustave Roussy, Villejuif, France.
• ⁹ École Normale Supérieure, PSL Research University, CNRS, Inserm, IBENS, Plateforme Génomique, 75005 Paris, France.
• ¹⁰ LOMA, Université de Bordeaux, CNRS, UMR 5798, F-33405 Talence, France.