[Profile of neovascular glaucoma in Senegalese patients]

J Fr Ophtalmol. 2018 Sep;41(7):637-641. doi: 10.1016/j.jfo.2017.11.040. Epub 2018 Aug 27.
[Article in French]

Abstract

Objective: To describe the etiologies, clinical presentation and therapeutic management of neovascular glaucoma (NVG) in Senegalese patients.

Patients and methods: We retrospectively studied the records of patients followed for NVG between 1993 and 2016. We included eyes with Iridis rubeosis with or without ocular hypertension. We recorded age, sex, medical and ophthalmologic history, results of the eye examination, treatment modalities broken up into hospitalisation, procedural interventions and number of antiglaucoma medications prescribed. The data analysis was performed by epi-info 7.

Results: Forty-eight eyes of 44 patients were included. The mean age was 59.7 years and sex ratio 2.1. Etiologies were type 2 diabetes in 31.8 % cases and central retinal vein occlusion in 16.6 % cases. All eyes were blind. Eye pain was present in 75 % of eyes, a limbal flush in 29.1 % of eyes and mydriasis in 31.25 % of eyes. Mean intraocular pressure was 49.7mmHg. Corneal edema occured in 54.1 % of eyes. Fundus examination showed proliferative retinopathy in 14.5 %. Treatment required hospitalisation for 43.75 % of patients. Therapeutic procedures were cyclocryoapplication for 31.25 % of eyes, retrobulbar xylo-alcohol injection for 14.5 % of eyes and panretinal laser photocoagulation (PRP) for 12.5 % eyes. Antiglaucoma preparations were used in dual therapy for 29 % of eyes, in triple therapy and quadruple therapy for 25 % of eyes each.

Discussion: The etiologies are comparable to those described in the literature. The diagnosis was late and treatment limited by adverse economic conditions.

Conclusion: NVG in Senegalese patients is an affection of men in their sixties. It is responsible for irreversible painful blindness for which treatment is difficult - thus the interest in prevention by strict monitoring and prompt treatment of any retinal ischemia.

Keywords: Central retinal vein occlusion; Diabetes; Diabéte; Glaucome néovasculaire; Iridis rubeosis; Ischemia; Ischémie; Neovascular glaucoma; Occlusion de la veine centrale de la rétine; Rubéose irienne; Senegalese; Sénégalais.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetic Retinopathy / epidemiology
  • Female
  • Glaucoma, Neovascular* / diagnosis
  • Glaucoma, Neovascular* / epidemiology
  • Glaucoma, Neovascular* / etiology
  • Glaucoma, Neovascular* / therapy
  • Humans
  • Male
  • Middle Aged
  • Retinal Vein Occlusion / complications
  • Retinal Vein Occlusion / epidemiology
  • Retrospective Studies
  • Senegal / epidemiology
  • Vitreoretinopathy, Proliferative / epidemiology
  • Young Adult