Sustained complete response of recurrent glioblastoma to combined checkpoint inhibition in a young patient with constitutional mismatch repair deficiency

Pediatr Blood Cancer. 2018 Dec;65(12):e27389. doi: 10.1002/pbc.27389. Epub 2018 Aug 29.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents, Immunological / therapeutic use*
  • Brain Neoplasms / complications
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / genetics
  • Child, Preschool
  • Colorectal Neoplasms / complications
  • Glioblastoma / drug therapy*
  • Glioblastoma / genetics
  • Humans
  • Ipilimumab / therapeutic use
  • Male
  • Neoplasm Recurrence, Local / drug therapy*
  • Neoplasm Recurrence, Local / genetics
  • Neoplastic Syndromes, Hereditary / complications
  • Nivolumab / therapeutic use

Substances

  • Antineoplastic Agents, Immunological
  • Ipilimumab
  • Nivolumab

Supplementary concepts

  • Turcot syndrome