Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy

Jeffrey S Marschall; George M Kushner; Brian S Shumway

doi:10.4103/jomfp.JOMFP_161_17

Aggressive histologic features do not predict biologic behavior in melanotic neuroectodermal tumor of infancy

J Oral Maxillofac Pathol. 2018 May-Aug;22(2):260-262. doi: 10.4103/jomfp.JOMFP_161_17.

Authors

Jeffrey S Marschall¹, George M Kushner¹, Brian S Shumway¹

Affiliation

¹ Department of Surgical and Hospital Dentistry, University of Louisville School of Dentistry, Louisville, Kentucky, USA.

Abstract

While generally benign, occasional aggressive histologic features in the melanotic neuroectodermal tumor of infancy (MNTI) have been used to justify a diagnosis of malignancy; this could lead to overtreatment. We report a case with presumed aggressive histologic features that did not recur following conservative treatment. This adds evidence that histologic features are not predictive of clinical behavior in MNTI.

Keywords: CD99; Ki-67; malignant; melanotic neuroectodermal tumor; necrosis.

Publication types

Case Reports