Neurosarcoidosis Presenting with Obstructive Hydrocephalus Successfully Treated with Endoscopic Third Ventriculostomy

Intern Med. 2019 Jan 1;58(1):105-108. doi: 10.2169/internalmedicine.1259-18. Epub 2018 Aug 24.

Abstract

A 58-year-old Japanese woman complained of unstable gait and dizziness lasting for a month. She had been diagnosed histologically with pulmonary and cutaneous sarcoidosis and attended outpatient clinics for routine checkups. Head computed tomography and magnetic resonance imaging (MRI) indicated obstructive hydrocephalus caused by a contrast-enhanced lesion in the cerebral aqueduct. The patient underwent endoscopic third ventriculostomy and a biopsy of the lesion, leading to the diagnosis of neurosarcoidosis. This was a rare case of neurosarcoidosis presenting with obstructive hydrocephalus that was treated with endoscopic third ventriculostomy and diagnosed histologically via an intraoperative biopsy.

Keywords: endoscopic third ventriculostomy; neurosarcoidosis; obstructive hydrocephalus; sarcoidosis.

Publication types

  • Case Reports

MeSH terms

  • Central Nervous System Diseases / surgery*
  • Female
  • Humans
  • Hydrocephalus / etiology*
  • Middle Aged
  • Sarcoidosis / surgery*
  • Third Ventricle / pathology
  • Treatment Outcome
  • Ventriculostomy / methods*

Supplementary concepts

  • Neurosarcoidosis