Cutaneous adverse drug reaction after apomorphine infusion, possibly caused by a systemic type IV hypersensitivity reaction to sodium metabisulfite: Report of 2 cases

Contact Dermatitis. 2018 Nov;79(5):316-318. doi: 10.1111/cod.13058. Epub 2018 Aug 19.

Authors

Robbert W K Borgemeester¹, Teus van Laar¹, Marie L A Schuttelaar²

Affiliations

¹ Parkinson Expertise Centre, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
² Department of Dermatology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

PMID: 30123968
DOI: 10.1111/cod.13058

No abstract available

Keywords: CAS no. 7681-57-4; allergy; apomorphine; delayed-type hypersensitivity; sodium metabisulfite; systemic; type IV hypersensitivity.

Publication types

Case Reports

MeSH terms

Adult
Aged
Apomorphine / therapeutic use*
Dopamine Agonists / therapeutic use*
Drug Eruptions / etiology*
Drug Hypersensitivity / etiology
Female
Humans
Hypersensitivity, Delayed / chemically induced*
Infusions, Subcutaneous
Male
Parkinson Disease / drug therapy*
Patch Tests
Preservatives, Pharmaceutical / adverse effects*
Sulfites / adverse effects*

Substances

Dopamine Agonists
Preservatives, Pharmaceutical
Sulfites
sodium metabisulfite
Apomorphine