Recurrent kidney stones in a child with Lesch-Nyhan syndrome: Answers

Pediatr Nephrol. 2019 Mar;34(3):425-427. doi: 10.1007/s00467-018-4037-9. Epub 2018 Aug 15.
No abstract available

Keywords: Allopurinol; Lesch-Nyhan syndrome; Purine metabolism.

Publication types

  • Case Reports

MeSH terms

  • Allopurinol / adverse effects
  • Child, Preschool
  • Fluid Therapy*
  • Humans
  • Hydrogen-Ion Concentration
  • Hypoxanthine Phosphoribosyltransferase / deficiency*
  • Hypoxanthine Phosphoribosyltransferase / genetics
  • Kidney / diagnostic imaging
  • Kidney / metabolism
  • Kidney Calculi / diagnostic imaging
  • Kidney Calculi / etiology
  • Kidney Calculi / metabolism
  • Kidney Calculi / therapy*
  • Lesch-Nyhan Syndrome / complications*
  • Lesch-Nyhan Syndrome / drug therapy
  • Lesch-Nyhan Syndrome / metabolism
  • Lesch-Nyhan Syndrome / urine
  • Male
  • Mutation
  • Potassium Citrate / administration & dosage
  • Recurrence
  • Renal Elimination
  • Ultrasonography
  • Urine / chemistry
  • Xanthine / chemistry
  • Xanthine / metabolism*
  • Xanthine / urine
  • Xanthine Oxidase / antagonists & inhibitors
  • Xanthine Oxidase / metabolism

Substances

  • Xanthine
  • Allopurinol
  • Xanthine Oxidase
  • Hypoxanthine Phosphoribosyltransferase
  • Potassium Citrate