Fluorescent probes for chloride ions in biological samples

Fengyuan Zhang; Chen Ma; Yaya Wang; Wei Liu; Xiaoyan Liu; Haixia Zhang

doi:10.1016/j.saa.2018.07.060

Fluorescent probes for chloride ions in biological samples

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Dec 5:205:428-434. doi: 10.1016/j.saa.2018.07.060. Epub 2018 Jul 21.

Authors

Fengyuan Zhang¹, Chen Ma², Yaya Wang², Wei Liu², Xiaoyan Liu², Haixia Zhang³

Affiliations

¹ College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China; School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China.
² College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
³ College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China. Electronic address: liuxiaoy@lzu.edu.cn.

PMID: 30053636
DOI: 10.1016/j.saa.2018.07.060

Abstract

As one of the most widespread anions, chloride ion largely existed in the water sources as well as living organism. Therefore, determination of chloride ions in biological samples is evidently important. Herein, we developed two analogous fluorescence probes BeQ1 and BeQ2 for the sensitive detection of chloride ions. The chloride ions in biological samples were determined by a direct and simple method with the detection limit of 46 and 66 μM respectively. In addition, the probes were found having the two-photon excitation property.

Keywords: Biological samples; Chloride ions; Fluorescent probe; Two-photon absorption.

MeSH terms

Chlorides / analysis*
Chlorides / chemistry
Fluorescent Dyes / chemistry*
Humans
Limit of Detection
Spectrometry, Fluorescence / methods*

Substances

Chlorides
Fluorescent Dyes