Leptospirosis as Cause of Febrile Icteric Illness, Burkina Faso

Emerg Infect Dis. 2018 Aug;24(8):1569-1572. doi: 10.3201/eid2408.170436.

Abstract

Patients in Burkina Faso who sought medical attention for febrile jaundice were tested for leptospirosis. We confirmed leptospirosis in 27 (3.46%) of 781 patients: 23 (2.94%) tested positive using serologic assays and 4 (0.51%) using LipL32 PCR. We further presumed leptospirosis in 16 (2.82%) IgM-positive specimens.

Keywords: Burkina Faso; ELISA; MAT; PCR; West Africa; bacteria; febrile illness; icteric; jaundice; leptospirosis.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Bacterial / blood*
  • Burkina Faso / epidemiology
  • Child
  • DNA, Bacterial / genetics*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Fever / diagnosis
  • Fever / microbiology
  • Fever / physiopathology
  • Humans
  • Jaundice / diagnosis
  • Jaundice / epidemiology*
  • Jaundice / microbiology
  • Leptospira / classification
  • Leptospira / genetics
  • Leptospira / immunology
  • Leptospira / isolation & purification*
  • Leptospirosis / diagnosis
  • Leptospirosis / epidemiology*
  • Leptospirosis / microbiology
  • Male
  • Polymerase Chain Reaction
  • Serogroup

Substances

  • Antibodies, Bacterial
  • DNA, Bacterial