Chronic lung disease, lung regeneration and future therapeutic strategies

Chronic Dis Transl Med. 2018 Jun 11;4(2):103-108. doi: 10.1016/j.cdtm.2018.05.001. eCollection 2018 Jun.

Abstract

Chronic lung diseases have been recognized as one of the world's leading causes of death in recent decades. Lacking effective treatments brings the patients not only bad quality of life but also higher risk for lung cancer development. By increasing the understanding of deeper mechanism of how lung develops and regenerates, researchers now focus on studying lung regenerative medicine, aiming to apply different and more efficient therapies to treat chronic lung diseases. This review will provide a wide picture of both basic lung developmental, regeneration mechanism and different designed strategies for treating chronic lung diseases in the future decades.

Keywords: Chronic obstructive pulmonary disease; Lung developmental mechanism; Regeneration medicines.