Reoperation for left atrioventricular valve failure in repaired atrioventricular septal defect: Can more valves be preserved in the current era?

J Card Surg. 2018 Aug;33(8):458-465. doi: 10.1111/jocs.13766. Epub 2018 Jul 2.

Abstract

Objective: Left atrio-ventricular valve (LAVV) regurgitation after repair of an atrio-ventricular septal defect (AVSD) may necessitate further surgery. However, redo-LAVV repair remains challenging. We sought to determine if more LAVV valves are preserved in the current era, and analyze early and longer-term results.

Patients: All consecutive patients with repaired AVSD who underwent redo-LAVV surgery from January 2004 to April 2017 were included. Patients with single ventricles, atrial isomerism, and complex associated anomalies were excluded.

Methods: This was a single-center study using retrospective chart review and an institutional database for follow-up information. Data analyzed included number and year of primary AVSD and redo-LAVV operation, presence of trisomy 21, morphology of AVSD, mortality, and reoperation. Univariate analysis included repair and replacement rates and early and long-term survival.

Results: During the study period 36 redo-LAVV operations were performed, with repair in 28 and replacement in eight. The number of redo-operations increased from 13 in the first part to 23 in the second part of the study. The rate of LAVV preservation significantly increased over time (54% vs 91%, P < 0.01), and was not affected by morphology of AVSD or trisomy 21. There was one in-hospital death at Day 42 and overall estimated survival was 94.5% at 5 years. Freedom from reoperation after redo-LAVV repair was 87% at 5 years with no significant difference between repair and replacement groups.

Conclusion: In the current era, more LAVVs can be preserved at the time of redo-operation with excellent early and long-term survival and acceptable reoperation rates. LAVV morphology and presence of trisomy 21 did not affect outcome.

Keywords: AVSD; LAVV re-operation; LAVV repair.

MeSH terms

  • Cardiac Surgical Procedures / mortality
  • Cardiac Surgical Procedures / statistics & numerical data
  • Female
  • Heart Septal Defects, Ventricular / surgery*
  • Heart Valve Diseases / epidemiology
  • Heart Valve Diseases / surgery*
  • Humans
  • Male
  • Organ Sparing Treatments / statistics & numerical data
  • Postoperative Complications / epidemiology
  • Postoperative Complications / surgery*
  • Reoperation / mortality
  • Reoperation / statistics & numerical data
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome