Skin lesions in preterm and term newborns from Southern Italy and their relationship to neonatal, parental and pregnancy-related variables

G Ital Dermatol Venereol. 2019 Aug;154(4):400-404. doi: 10.23736/S0392-0488.18.06068-6. Epub 2018 Jun 29.

Abstract

Background: Cutaneous lesions are common in the neonatal period and usually physiological, transient and self-limited; infrequently, they are pathological and require treatment and collaboration between dermatologists and neonatologists. Particular conditions, like prematurity, can influence onset, type and evolution of cutaneous manifestations. Of the several articles in literature about skin findings in newborns, only few were performed in Southern European countries. We aimed to investigate dermatological findings in a sample of neonates within the first 7 days of life and to evaluate the association between skin lesions and neonatal, parental or pregnancy-related variables.

Methods: A total of 259 newborns, hospitalized in the Department of Pediatrics and Neonatal Intensive Care Unit, Barone Romeo Hospital, Patti (Messina), Italy, during a six months period, were examined. All skin findings were recorded and information on neonatal, parental and pregnancy-related variables was collected and analyzed to detect statistically significant associations.

Results: Skin lesions were present in 181 newborns (69.88%). Their frequency was significantly higher in those born to primigravida mothers (P=0.024). Erythema toxicum neonatorum prevalence was significantly higher (P=0.006) in term newborns.

Conclusions: Skin findings are frequent in newborns and often cause concern in parents and physicians without specific experience. Thus, it is important to know and identify them promptly to avoid unnecessary diagnostic and therapeutic procedures.

MeSH terms

  • Adolescent
  • Adult
  • Cross-Sectional Studies
  • Erythema / epidemiology*
  • Erythema / pathology
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology*
  • Infant, Newborn, Diseases / pathology
  • Infant, Premature
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / pathology
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Parents
  • Pregnancy
  • Prevalence
  • Risk Factors
  • Skin Diseases / epidemiology*
  • Skin Diseases / pathology
  • Young Adult