Executive summary of clinical practice guideline for the management of invasive diseases caused by Aspergillus: 2018 Update by the GEMICOMED-SEIMC/REIPI
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Oct;37(8):535-541.
doi: 10.1016/j.eimc.2018.03.018.
Epub 2018 Jun 28.
[Article in
English,
Spanish]
Authors
Carolina Garcia-Vidal
1
, Ana Alastruey-Izquierdo
2
, Manuela Aguilar-Guisado
3
, Jordi Carratalà
4
, Carmen Castro
5
, Mario Fernández-Ruiz
6
, José María Aguado
6
, José María Fernández
7
, Jesús Fortún
8
, José Garnacho-Montero
9
, Joan Gavaldà
10
, Carlota Gudiol
4
, Jesús Guinea
11
, Alicia Gómez-López
2
, Patricia Muñoz
11
, Javier Pemán
12
, Montserrat Rovira
13
, Isabel Ruiz-Camps
10
, Manuel Cuenca-Estrella
2
Affiliations
- 1 Servicio de Enfermedades Infecciosas, Hospital Clínic, Barcelona, IDIBAPS, Universitat de Barcelona, Spain. Electronic address: CGARCIAV@clinic.cat.
- 2 Laboratorio de referencia e investigación en Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Spain.
- 3 Department of Infectious Diseases, Microbiology, and Preventive Medicine, University Hospital Virgen del Rocío-Institute of Biomedicine of Seville (IBiS), Seville, Spain.
- 4 Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge, ICO, IDIBELL, Universitat de Barcelona, Spain.
- 5 UCEIM, Unidad Clínica de Enfermedades Infecciosas y Microbiología, HU Valme, Sevilla, Spain.
- 6 Unidad de Enfermedades Infecciosas, Hospital Universitario "12 de Octubre", Instituto de Investigación Hospital "12 de Octubre" (i+12), Universidad Complutense, Madrid, Spain.
- 7 Servicio de Pediatría, Hospital Universitario La Fe, Valencia, Spain.
- 8 Servicio de Enfermedades Infecciosas, Hospital Universitario Ramón y Cajal, Madrid, Spain.
- 9 Unidad Clínica de Cuidados Intensivos, Hospital Universitario Virgen Macarena, Sevilla, Spain.
- 10 Servicio de Enfermedades Infecciosas, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
- 11 Servicio de Microbiología Clínica y Enfermedades Infecciosas-VIH, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Spain.
- 12 Servicio de Microbiología, Hospital Universitario La Fe, Valencia, Spain.
- 13 Servicio de Hematología, Hospital Clínic, Barcelona, IDIBAPS, Universitat de Barcelona, Spain.
Abstract
Aspergillus infection is a significant cause of morbi-mortality in an at-risk population. The Study Group of Fungal Infections (GEMICOMED) from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) has reviewed announcements made in invasive aspergillosis management. We have organized our recommendations in such a way as to provide a guide in resolving different clinical situations concerning the entire spectrum of invasive diseases caused by Aspergillus in various populations. Diagnostic approach, treatment and preventions strategies are outlined. It is not our aim that these guidelines supplant clinical judgment with respect to specific patients; however, it is our objective to perform a comprehensive summary of quality of care evidence for invasive aspergillosis management in different settings.
Keywords:
Aspergillosis; Aspergilosis; Isavuconazol; Isavuconazole; Manejo clínico; Monitorización de noveles; Therapeutic drug monitoring; Tratamiento; Treatment; Voriconazol; Voriconazole.
Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.
MeSH terms
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Aspergillosis / diagnosis*
-
Aspergillosis / drug therapy*
-
Humans
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Invasive Fungal Infections / diagnosis*
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Invasive Fungal Infections / drug therapy*