Introducing medical genetics services in Ethiopia using the MiGene Family History App

Genet Med. 2019 Feb;21(2):451-458. doi: 10.1038/s41436-018-0069-6. Epub 2018 Jun 11.

Abstract

Purpose: Almost all low-income countries and many middle-income countries lack the capacity to deliver medical genetics services. We developed the MiGene Family History App (MFHA), which assists doctors with family history collection and population-level epidemiologic analysis. The MFHA was studied at St. Paul's Hospital in Addis Ababa, Ethiopia.

Methods: A needs assessment was used to assess Ethiopian physicians' experience with genetics services. The MFHA then collected patient data over a 6-month period.

Results: The majority of doctors provide genetics services, with only 16% reporting their genetics knowledge is sufficient. A total of 1699 patients from the pediatric ward (n = 367), neonatal intensive care unit (NICU) (n = 477), and antenatal clinic (n = 855) were collected using the MFHA with a 4% incidence of a MFHA-screened condition present. The incidence was 11.7% in the pediatric ward, 3% in the NICU, and 0.5% in the antenatal clinic. Heart malformations (5.5% of patients) and trisomy 21 (4.4% of patients) were the most common conditions in the pediatric ward.

Conclusion: Medical genetics services are needed in Ethiopia. As other countries increase their genetics capacity, the MFHA can provide fundamental genetics services and collect necessary epidemiologic data.

Keywords: Community genetics; Family health history; Global health; Mobile health; Noncommunicable diseases.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Epidemiologic Methods
  • Ethiopia
  • Female
  • Genetic Services*
  • Humans
  • Male
  • Medical History Taking*
  • Mobile Applications*
  • Needs Assessment
  • Physicians
  • Surveys and Questionnaires