The involvement of ROS generation on Epoxiconazole-induced toxicity in HCT116 cells

Pestic Biochem Physiol. 2018 Jun:148:62-67. doi: 10.1016/j.pestbp.2018.03.014. Epub 2018 Mar 28.
No abstract available

Keywords: DNA fragmentation; Epoxiconazole; HCT116; Oxidative stress.

MeSH terms

  • Acetylcysteine / pharmacology
  • Comet Assay
  • DNA Damage
  • Epoxy Compounds / toxicity*
  • Fungicides, Industrial / toxicity*
  • HCT116 Cells
  • Humans
  • Lipid Peroxidation
  • Membrane Potential, Mitochondrial / drug effects
  • Mitochondria / drug effects
  • Oxidative Stress
  • Reactive Oxygen Species / metabolism*
  • Triazoles / toxicity*

Substances

  • Epoxy Compounds
  • Fungicides, Industrial
  • Reactive Oxygen Species
  • Triazoles
  • epoxiconazole
  • Acetylcysteine