Association of anthropometric measures and cardio-metabolic risk factors in normal-weight children and adolescents: the CASPIAN-V study

J Pediatr Endocrinol Metab. 2018 Aug 28;31(8):847-854. doi: 10.1515/jpem-2018-0018.

Abstract

Background: The present study aims to explore the association of anthropometric indices and cardio-metabolic risk factors in normal-weight children and adolescents.

Methods: This cross-sectional nationwide study was conducted in 2015 among 4200 Iranian school students aged 7-18 years. They were selected using a multi-stage cluster random sampling method. Anthropometric indices and cardio-metabolic risk factors including fasting blood glucose (FBG), lipid profile and blood pressure (BP) were measured using standard protocols.

Results: The response rate was 91.5%. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) had a significant positive correlation with waist circumference (WC), hip circumference (HC) and body mass index (BMI) in boys and girls. HDL-C had a significant inverse correlation with WC, HC and BMI in boys. For each unit increase in WC, HC and BMI, the risk of elevated DBP significantly increased by 2%, 1% and 11%, respectively. Likewise, for each unit increase in WC, HC and BMI, the risk of elevated BP significantly raised by 2%, 1% and 10%, respectively. For each unit increase in WC, the risk of metabolic syndrome increased by 7%.

Conclusions: Anthropometric indices are considered an easy, non-invasive tool for the prediction of cardio-metabolic risk factors in normal-weight children and adolescents.

Keywords: anthropometric indices; body mass index; cardio-metabolic risk factors; children and adolescents; waist and hip circumference.

MeSH terms

  • Adolescent
  • Biomarkers / metabolism
  • Blood Pressure*
  • Body Mass Index*
  • Cardiovascular Diseases / etiology*
  • Child
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Metabolic Syndrome / etiology*
  • Obesity / complications*
  • Prognosis
  • Waist Circumference*
  • Waist-Hip Ratio

Substances

  • Biomarkers