Noninferiority studies: Not inherently unethical

Madeline McCarren; Todd P Semla

doi:10.2146/ajhp180052

Noninferiority studies: Not inherently unethical

Am J Health Syst Pharm. 2018 Jun 15;75(12):915-918. doi: 10.2146/ajhp180052.

Authors

Madeline McCarren¹, Todd P Semla^{2

3}

Affiliations

¹ Pharmacy Benefits Management, U.S. Department of Veterans Affairs, Hines, IL. madeline.mccarren@va.gov.
² National PBM Clinical Pharmacy, U.S. Department of Veterans Affairs, Hines, IL.
³ Departments of Medicine and Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL.

PMID: 29880527
DOI: 10.2146/ajhp180052

No abstract available

Keywords: clinical trials; comparative effectiveness research; drug evaluation; equivalence trial; noninferiority trial; pragmatic clinical trials.

MeSH terms

Equivalence Trials as Topic*
Ethics, Pharmacy*
Humans
Pharmaceutical Preparations / standards
Research Design / standards
Therapeutic Equivalency
Treatment Outcome

Substances

Pharmaceutical Preparations