Misdiagnosis of Bordetella bronchiseptica Respiratory Infection as Bordetella pertussis by Multiplex Molecular Assay

Clin Infect Dis. 2018 Nov 28;67(12):1919-1921. doi: 10.1093/cid/ciy469.

Abstract

Multiplex polymerase chain reaction (PCR) tests are useful for the rapid detection of pathogens, though diagnostic challenges may arise. We report 2 immunocompromised patients with Bordetella bronchiseptica respiratory infection misdiagnosed as Bordetella pertussis using PCR, including discussion of transmission, diagnostic testing, clinical implications, and infection control considerations.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bordetella Infections / diagnosis*
  • Bordetella Infections / drug therapy
  • Bordetella Infections / microbiology
  • Bordetella bronchiseptica / genetics
  • Bordetella bronchiseptica / isolation & purification
  • Bordetella pertussis / genetics
  • Bordetella pertussis / isolation & purification
  • Cross Reactions
  • DNA, Bacterial / genetics
  • Diagnostic Errors*
  • False Positive Reactions
  • Female
  • Humans
  • Immunocompromised Host
  • Male
  • Middle Aged
  • Multiplex Polymerase Chain Reaction
  • Respiratory Tract Infections / diagnosis*
  • Respiratory Tract Infections / microbiology

Substances

  • DNA, Bacterial