Safety of Laparoscopic Surgery for Colorectal Cancer in Patients with Severe Comorbidities

Anticancer Res. 2018 Jun;38(6):3767-3772. doi: 10.21873/anticanres.12659.

Abstract

Background/aim: Previous studies have shown that laparoscopic colorectal cancer surgery is highly safe and effective compared to laparotomy. However, whether laparoscopic colorectal cancer surgery can be safely performed in patients with severe comorbidities remains unclear. The aim of this study was to evaluate the safety of laparoscopic colorectal cancer surgery in patients with severe comorbidities.

Patients and methods: A total of 82 consecutive patients with colorectal cancer who underwent laparoscopic surgery were retrospectively divided into two groups according to whether they had severe comorbidity (50 patients) or non-severe comorbidity (32 patients). An age-adjusted Charlson comorbidity index of ≥6 was defined as severe comorbidity.

Results: Operative time, blood loss, and rate of conversion to laparotomy did not differ between the groups. Postoperative complications and the length of the postoperative hospital stay also did not differ significantly between the groups.

Conclusion: Laparoscopic colorectal cancer surgery is feasible and safe, even in patients with severe comorbidities.

Keywords: Colorectal cancer; age-adjusted Charlson comorbidity index; comorbidity; laparoscopic surgery.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases / epidemiology
  • Colorectal Neoplasms / epidemiology
  • Colorectal Neoplasms / surgery*
  • Comorbidity
  • Feasibility Studies
  • Female
  • Humans
  • Kidney Diseases / epidemiology
  • Laparoscopy / methods*
  • Liver Diseases / epidemiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Severity of Illness Index
  • Treatment Outcome