Attempts to implicate viruses in myasthenia gravis

Neurology. 1985 Feb;35(2):185-92. doi: 10.1212/wnl.35.2.185.

Abstract

We investigated the hypothesis that a persistent viral infection of the thymus gland might trigger the autoimmune disease myasthenia gravis (MG). Thymus glands of nine patients with recent onset of MG were studied by a variety of techniques to detect the presence of occult viruses. No evidence of viral infection was found.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Autoimmune Diseases / microbiology
  • Child
  • DNA Viruses
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Male
  • Microbiological Techniques
  • Middle Aged
  • Muridae
  • Myasthenia Gravis / microbiology*
  • Newcastle disease virus
  • Organ Culture Techniques
  • Poliovirus
  • RNA Viruses
  • Thymus Gland / microbiology*
  • Virus Diseases / microbiology