Disorders of the Diaphragm

Clin Chest Med. 2018 Jun;39(2):345-360. doi: 10.1016/j.ccm.2018.01.012.

Abstract

Pathologic processes that involve the central nervous system, phrenic nerve, neuromuscular junction, and skeletal muscle can impair diaphragm function. When these processes are of sufficient severity to cause diaphragm dysfunction, respiratory failure may be a consequence. This article reviews basic diaphragm anatomy and physiology and then discusses diagnostic and therapeutic approaches to disorders that result in unilateral or bilateral diaphragm dysfunction. This discussion provides a context in which disorders of the diaphragm and their implications on respiratory function can be better appreciated.

Keywords: Diaphragm dysfunction; Diaphragm eventration; Diaphragm ultrasound.

Publication types

  • Review

MeSH terms

  • Diaphragm / diagnostic imaging
  • Diaphragm / physiopathology*
  • Humans
  • Neuromuscular Junction / physiopathology
  • Phrenic Nerve / physiopathology
  • Respiratory Insufficiency / physiopathology