Foot-and-Mouth Disease in the Middle East Caused by an A/ASIA/G-VII Virus Lineage, 2015-2016

Emerg Infect Dis. 2018 Jun;24(6):1073-1078. doi: 10.3201/eid2406.170715.

Abstract

Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015-2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent. Changes in a critical antigenic site within capsid viral protein 1 suggest possible evolutionary pressure caused by an intensive vaccination program.

Keywords: A/ASIA/G-VII virus lineage; FMD; FMDV; Indian subcontinent; Middle East; aphthovirus; cattle; epidemiology; foot-and-mouth disease; foot-and-mouth disease virus; outbreaks; vaccination; vaccines; viruses; zoonoses.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Capsid Proteins / genetics
  • Disease Outbreaks*
  • Foot-and-Mouth Disease / epidemiology*
  • Foot-and-Mouth Disease / history
  • Foot-and-Mouth Disease / virology*
  • Foot-and-Mouth Disease Virus / classification*
  • Foot-and-Mouth Disease Virus / genetics*
  • Genetic Variation
  • History, 21st Century
  • Middle East / epidemiology
  • Phylogeny
  • Sequence Analysis, DNA

Substances

  • Capsid Proteins