Use of radioiodine-131 scan to measure influence of surgical discipline, practice, and volume on residual thyroid tissue after total thyroidectomy for differentiated thyroid carcinoma

Head Neck. 2018 Oct;40(10):2129-2136. doi: 10.1002/hed.25204. Epub 2018 May 13.

Abstract

Background: Our study's purpose is to determine the influence of surgical discipline, surgeon site, and volume on remnant thyroid tissue visualized on radioactive iodine-131 (I-131) scans after total thyroidectomy and I-131 ablation in patients with well-differentiated thyroid carcinomas.

Methods: We retrospectively reviewed all cases of patients who received I-131 therapeutic ablation and postablation radioactive I-131 scans at our center after thyroidectomy to calculate the fraction of administered dose multiplied by 1000 (UDR1000).

Results: The remnant thyroid tissue (ie, the UDR1000), between academic and community surgeons was 0.471 (±0.705) and 1.190 (±2.487), respectively (P = .001). The UDR1000 between otolaryngology-head and neck surgery and general surgery was 0.654 (±1.575) and 1.043 (±1.625), respectively (P = .159). The UDR1000 partitioned by patient frequencies of <10, 10 to 19, and ≥20 patients yielded 1.255 (±2.554), 0.926 (±2.084), and 0.467 (±0.721), respectively (P = .003).

Conclusion: Our study found statistically significant differences in residual thyroid tissue visualized on radioactive I-131 scans based on surgeon parameters.

Keywords: differentiated thyroid carcinoma; iodine-131; papillary thyroid carcinoma; radioactive iodine; thyroidectomy.

Publication types

  • Comparative Study

MeSH terms

  • Ablation Techniques
  • Academic Medical Centers
  • Adenocarcinoma, Follicular / surgery
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Papillary / surgery
  • Female
  • General Surgery
  • Hospitals, Community
  • Hospitals, High-Volume
  • Hospitals, Low-Volume
  • Humans
  • Iodine Radioisotopes / administration & dosage*
  • Male
  • Middle Aged
  • Nova Scotia
  • Otolaryngology
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Radionuclide Imaging
  • Retrospective Studies
  • Surgeons*
  • Thyroid Gland / diagnostic imaging*
  • Thyroid Gland / pathology
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy*
  • Young Adult

Substances

  • Iodine Radioisotopes