DNA hybridization enables the three-dimensional assembly of Au nanoparticles and streptavidin. The high-density DNA-modified Au nanoparticles were stable to nonspecific binding of streptavidin. Structural and melting investigations on the assemblies showed their formation was reversible.
Keywords: DNA structures; nanostructures; oligonucleotides; proteins; small-angle X-ray scattering.
© 2001 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.