Hematopoietic reconstitution after autologous hematopoietic stem cell transplantation: do CD45 (+) CD34 (+) CD38 (-) progenitors really matter in real life?

G Venton; P Suchon; J Colle; C Baier; F Sanderson; P Poullin; V Ivanov; C Mercier; L Farnault; P Roche; R Arcani; R Fanciullino; C Brunet; P J M Philip; R Costello

doi:10.1016/j.transci.2018.04.021

Hematopoietic reconstitution after autologous hematopoietic stem cell transplantation: do CD45 (+) CD34 (+) CD38 (-) progenitors really matter in real life?

Transfus Apher Sci. 2018 Jun;57(3):406-408. doi: 10.1016/j.transci.2018.04.021. Epub 2018 Apr 24.

Authors

G Venton¹, P Suchon², J Colle¹, C Baier³, F Sanderson⁴, P Poullin⁴, V Ivanov⁵, C Mercier⁶, L Farnault⁵, P Roche⁵, R Arcani⁵, R Fanciullino⁷, C Brunet⁸, P J M Philip⁹, R Costello¹⁰

Affiliations

¹ INSERM, UMR1090 TAGC,Marseille, F_13288,France; Aix-Marseille University, UMR1090 TAGC,Marseille, F_13288,France; Hematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, France.
² Hematology laboratory, La Timone, University Hospital of Marseille, France; UMR 1062 NORT, INSERM, Marseille France.
³ INSERM, UMR1090 TAGC,Marseille, F_13288,France.
⁴ Hematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, France; Apheresis and auto transfusion department, la Conception, University Hospital of Marseille, France.
⁵ Hematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, France.
⁶ Hematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, France; UMR-911 INSERM, Toxicokinetics andpharmacokinetics laboratory, pharmacological faculty, Marseille, France.
⁷ SMARTc Unit, Pharmacokinetics Laboratory, UMR_911 CRO2 AMU Marseille, France; Pharmacy Unit, La Conception University Hospital of Marseille, APHM, Marseille, France.
⁸ Hematology laboratory, La Conception, University Hospital of Marseille, France.
⁹ Cell therapy unit - The French Blood Establishment (EFS - Provence - Alpes Côte d'Azur - Corse)", Saint Laurent du Var, France.
¹⁰ INSERM, UMR1090 TAGC,Marseille, F_13288,France; Aix-Marseille University, UMR1090 TAGC,Marseille, F_13288,France; Hematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, France. Electronic address: regis.costello@ap-hm.fr.

PMID: 29709543
DOI: 10.1016/j.transci.2018.04.021

No abstract available

Publication types

Letter

MeSH terms

ADP-ribosyl Cyclase 1*
Adult
Antigens, CD34*
Autografts
Female
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells / metabolism*
Hematopoietic Stem Cells / pathology
Humans
Leukocyte Common Antigens*
Male
Membrane Glycoproteins*
Middle Aged
Multiple Myeloma* / blood
Multiple Myeloma* / pathology
Multiple Myeloma* / therapy

Substances

Antigens, CD34
Membrane Glycoproteins
Leukocyte Common Antigens
PTPRC protein, human
CD38 protein, human
ADP-ribosyl Cyclase 1