Barriers and Facilitators to the Deprescribing of Nonbenzodiazepine Sedative Medications Among Older Adults

Perm J. 2018:22:17-157. doi: 10.7812/TPP/17-157.

Abstract

Introduction: Nonbenzodiazepine sedative-hypnotic medications, or "Z-drugs," are commonly used to treat insomnia among older adults (≥ 65 years), despite a lack of evidence of long-term effectiveness and evidence linking long-term use with poor outcomes.

Objective: To understand patient and clinician barriers and facilitators to deprescribing, or discontinuation, of Z-drugs.

Methods: We conducted a qualitative interview study among older adults who received a deprescribing intervention and among their clinicians at Kaiser Permanente Northwest. Semistructured interviews explored perceived barriers and facilitators to successful deprescribing of Z-drugs. Interviews were audiorecorded with participant permission. Content was analyzed using QSR NVivo 10 software.

Results: From the perspectives of patients, the greatest challenges to deprescribing are factors related to their insomnia, including the need for effective treatment of their insomnia; health care system factors, including a desire for personalized approaches to care; and their own positive personal experiences with sedative medication use. From the clinician perspective, a lack of institutional structures and resources to support deprescribing, the attitudes and practices of previous clinicians, and patient-related factors such as dependence and a lack of alternatives to treat insomnia were the most important barriers to deprescribing.

Conclusions: Health care systems must provide individualized care that supports patient goals for restful sleep and quality of life while also providing evidence-based care that takes patient safety into account. To accomplish this, systems must support patients and clinicians and provide a multidisciplinary approach that addresses insomnia treatment, provides patient education about sedative medication use, and supports the discontinuation process.

MeSH terms

  • Aged
  • Attitude of Health Personnel
  • Deprescriptions*
  • Health Services Accessibility / standards*
  • Health Services for the Aged / standards*
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Patient Satisfaction
  • Qualitative Research
  • Quality of Life
  • Sleep Initiation and Maintenance Disorders / drug therapy*

Substances

  • Hypnotics and Sedatives