Artistic creativity and risk for schizophrenia, bipolar disorder and unipolar depression: a Swedish population-based case-control study and sib-pair analysis

Br J Psychiatry. 2018 Jun;212(6):370-376. doi: 10.1192/bjp.2018.23. Epub 2018 Apr 26.

Abstract

Background: Many studies have addressed the question of whether mental disorder is associated with creativity, but high-quality epidemiological evidence has been lacking.AimsTo test for an association between studying a creative subject at high school or university and later mental disorder.

Method: In a case-control study using linked population-based registries in Sweden (N = 4 454 763), we tested for associations between tertiary education in an artistic field and hospital admission with schizophrenia (N = 20 333), bipolar disorder (N = 28 293) or unipolar depression (N = 148 365).

Results: Compared with the general population, individuals with an artistic education had increased odds of developing schizophrenia (odds ratio = 1.90, 95% CI = [1.69; 2.12]) bipolar disorder (odds ratio = 1.62 [1.50; 1.75]) and unipolar depression (odds ratio = 1.39 [1.34; 1.44]. The results remained after adjustment for IQ and other potential confounders.

Conclusions: Students of artistic subjects at university are at increased risk of developing schizophrenia, bipolar disorder and unipolar depression in adulthood.Declaration of interestNone.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bipolar Disorder / epidemiology*
  • Case-Control Studies
  • Creativity*
  • Depressive Disorder, Major / epidemiology*
  • Educational Status
  • Female
  • Humans
  • Male
  • Middle Aged
  • Registries / statistics & numerical data*
  • Schizophrenia / epidemiology*
  • Siblings
  • Sweden / epidemiology
  • Young Adult